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2moro2nite Studies

WHAT DOES ALCOHOL DO TO THE BODY ?

Excessive alcohol intake has a wide range of effects on our bodies, many of which can contribute to hangover symptoms.

Some of these effects include:

  • Dehydration: Alcohol is a diuretic, this means you urinate more often when drinking alcohol and can become dehydrated. Dehydration is one of the causes of headaches, dizziness and thirst
  • Gastrointestinal effects: Alcohol causes irritation which in turn increases acid production. Increased acid production can causes nausea, vomiting, diarrhea and indigestion.
  • Electrolyte imbalance: Alcohol can affect your body's electrolyte levels
  • Hypoglycemia (low blood sugar): Consuming alcohol limits the production of glucose in the body which can lead to fatigue, dizziness and irritability.
  • Inflammation: Alcohol increase inflammation in the body which contributes to the malaise that people feel.
  • Immune system effects: Alcohol consumption may impair your immune system

N-ACETYL-CYSTEINE

N-acetyl-cysteine (NAC) is a derivative of L-Cysteine which is a non-essential amino acid. L-Cysteine is very important in the synthesis of Glutathione. NAC supplementation increases the production of Glutathione. Glutathione is a powerful antioxidant and co-factor in Phase 1 hepatic detoxification. Phase 1 liver detoxification consists of a group of enzymes that is the first line defence against toxins. Glutathione is needed in the production of these enzymes, these enzymes help neutralize toxins like ethanol and caffeine. Glutathione through above mentioned processes decreases oxidative stress, boosts the immune system and detoxifies the liver.

Studies have shown that NAC can reduce damage caused by toxins and improve liver function. Some studies have shown that NAC can decrease apoptosis (cell death), decrease endothelial dysfunction and prolong cell life.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241507/

https://pubmed.ncbi.nlm.nih.gov/24819310/

https://jissn.biomedcentral.com/articles/10.1186/1550-2783-2-2-38

L-THEANINE

Studies have shown that L-Theanine can improve cognitive function (memory and thinking skills)

https://pubmed.ncbi.nlm.nih.gov/21040626/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836118/

VITAMIN B1 (THIAMINE)

Alcoholism/increased alcohol intake can impair Thiamine levels. Symptoms of Thiamine deficiency include:

  • Fatigue
  • Reduced reflexes
  • Muscle weakness
  • Tingling feeling in arms and legs
  • Muscle weakness
  • Nausea and vomiting

Vitamin B1 also plays a key role in the maintenance of brain function.

https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/

VITAMIN B3 (NIACIN)

Alcohol consumption can inhibit the conversion of tryptophan to niacin

Sever niacin deficiency can lead to pellagra. Symptoms of pellagra include: vomiting, constipation or diarrhea, apathy, headache, fatigue, memory loss and depression.

https://ods.od.nih.gov/factsheets/Niacin-HealthProfessional/

VITAMIN B6 (PYRIDOXINE)

Pyridoxine creates neurotransmitters, which are important chemical messengers in the brain.

Pyridoxine is also responsible for energy regulation in the brain.

Pyridoxine is an important key in haemoglobin production, which is the protein that delivers oxygen to the cells and muscles in the body

https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

VITAMIN B12

Alcohol can decrease Vitamin B12 absorption in the gastrointestinal tract. Vitamin B12 can only be consumed the body cannot produce it's own Vitamin B12.

Vitamin B12 is essential in Red Blood Cell production, this means Vitamin B12 deficiency can lead to Anemia, which in turn can lead to tachycardia (irregular heartbeat), shortness of breath, weakness, fatigue and chest pain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257642/

https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=85&ContentID=P00080

VITAMIN C (ASCORBIC ACID)

Studies have shown that Vitamin C can stimulate the immune system by supporting cellular functions in both the innate and adaptive immune system.

Vitamin C also acts as an anti-oxidant with strong anti-inflammatory properties to protect the body against free radicals.

https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707683/#:~:text=Role%20of%20vitamin%20C%20in%20immune%20defense.,skin%20%5B36%2C37%5D

TRISODIUM CITRATE, SODIUM CHLORIDE, POTASSIUM CHLORIDE & MAGNESIUM 

Electrolytes are particles that carry a positive or negative electric charge. They regulate nerve and muscle function, hydrate the body, balance blood acidity and pressure, and help rebuild damaged tissue.

Alcohol consumption as mentioned before can affect electrolyte levels in the body.

https://www.medicalnewstoday.com/articles/153188

https://www.medicinenet.com/electrolytes/article.htm#which_drugs_or_supplements_interact_with_sodium_polystyrene_sulfonate-powder

SUCROSE (SUGAR)

Consuming alcohol can lead to hypoglycemia. Sugar increases glucose production.

https://pubmed.ncbi.nlm.nih.gov/13780317/

 

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