PregaNause™ Studies
Morning sickness is the nausea and vomiting that occurs during pregnancy. About 70% of women experience nausea and vomiting during the first trimester of pregnancy. Despite the name, the nausea can affect pregnant women any time of day. Morning sickness normally starts around the sixth week and ends by the end of the first trimester. Morning sickness is thought to be caused by an increase in pregnancy hormones such as oestrogen, progesterone and hCG, lower blood sugar levels and an increased sensitivity to smells.
Zingiber officinal (Gingerol)
Ginger have been used as a traditional remedy for nausea and vomiting for ages. Recent studies have shown that gingerol can inhibit 5HT3 and acetylcholine receptors. 5HT3 and acetylcholine receptor antagonist has strong antiemetic effects.
A double blind, randomised placebo-controlled trial with 141 patients between the age of 1 to 10 years showed that oral administration of ginger is effective and safe at improving vomiting in children.
https://onlinelibrary.wiley.com/doi/full/10.1111/apt.16404
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818021/#:~:text=Ginger%20is%20an%20ancient%20herb,and%20vomiting%20and%20is%20safe.
Lemon Bioflavonoids
Lemon is a type of citrus fruit. Lemon contains antioxidants called bioflavonoids. Bioflavonoids have been used in the treatment and prevention of some vestibular diseases. Studies have shown that Lemon bioflavonoids can decrease dizziness and help patients struggling with vertigo.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538675/
Vitamin B6 (Pyridoxine)
Vitamin B6, also known as pyridoxine, is a water-soluble vitamin needed in the body for several functions. The body cannot produce Vitamin B6, so it must be obtained from food or supplements.
Vitamin B6 has been used for decades in the treatment of nausea and vomiting during pregnanacy. Studies have shown that pyridoxine can be used as a single agent or in conjunction with other agents to control nausea and vomiting in pregnant women.
A study conducted with 342 women found that a daily supplement of Vitamin B6 significantly reduced the feeling of nausea after 5 days of treatment, compared to a placebo.
https://www.hindawi.com/journals/ogi/2013/927834/
https://www.mayoclinic.org/diseases-conditions/morning-sickness/diagnosis-treatment/drc-20375260
https://pubmed.ncbi.nlm.nih.gov/7573262/
