Valerian extract has shown to decrease sleep latency (the time it takes to fall asleep), improve sleep quality and decrease awakenings .
In a double blind study 44% of patients reported perfect sleep and 89% reported improved sleep.
In another double blind study where 121 patients either received a valerian root extract or the placebo results showed that the patients receiving the valerian root extract had a decrease in insomnia symptoms.
Another study has showed that insomnia can be triggered by the effects of stress.
Passionflower extract has shown a significant improvement in the management of Generalized Anxiety Disorder (GAD)
Passionflower extract is also used for stress and anxiety
In two studies consisting of 198 patients the efficacy of benzodiazepine and passionflower extract in the treatment of anxiety disorder was reviewed. One study showed that passionflower was as effective as benzodiaze0pines. the studies also showed a lower rate of drowsiness with passionflower extract compared with the benzodiazepines.
A double blind, placebo controlled investigation suggested that passionflower extract yields sleep benefits for patients with mild fluctuations in sleep quality
Multiple studies have found that supplementation with B vitamin can improve overall mental well-being.
In a randomized, double blind, placebo-controlled trial with 50 men, vitamin B supplementation compared with the placebo showed a significant reduction in the overall score on the depression, anxiety and stress scale.
Other studies have shown that supplementation with B vitamins can decrease subjective stress.
In a double blind, randomized, placebo-controlled trial results have shown significant improvement in stress related symptoms, sleep latency and sleep disturbance when L-Theanine and placebo was compared.
The above mention study showed that stress related symptoms (i.e. depression and anxiety) scores decrease and cognitive function scores improved after 4 weeks of L-Theanine treatment. L-Theanine treatment was safe and well complied with.